Question
A surveyor asks a technician why sterile storage is kept warmer, drier, and under positive air pressure compared with decontamination, and what happens if that pressure relationship is ever reversed. What is the correct explanation?
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Sterile storage is capped near 75 degrees F and 60 percent relative humidity under positive pressure because excess moisture can wick through a package's wrap and compromise sterility, and positive pressure pushes room air outward so airborne contaminants from adjoining spaces cannot migrate in and settle on stored packages. If the pressure relationship reverses, even briefly, unfiltered air from a less-clean area can be drawn into storage, which is treated as a real environmental excursion requiring investigation and, depending on duration, review of items stored during that window, not just a note in a log.
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